Spidey’s combos need to be built with the assists that you have. Use both assists for air grabs and at least 1 extender for combos and confirms. Most combos require zip OTGs for more damage (swing to web throw, ground series to web throw, stray confirms to web throw). For confirms off hits, ideally you should web throw for more damage but spider sting makes confirms easier.
Spidey’s combos are easy to learn but require timing inputs, especially for the OTG zip. It’s actually harder to get hits in to start any of his combos. If you’re using missiles assist, just do the basic swing combo to jump loops, sting/bite to assist + sj magic series. That also works for happy birthdays and although it’s not that damaging, you get a reset after the missiles OTG either of their characters.
You can check the link on my sig for more damaging combos with web throws, from raw web throws and a variety of assists as well as the fake TAC reset.