Wesker- He can get around her zoning and he has a better damage output. His ground gunshot will beat out low voltage. Gunshot also stops peekaboo.
Dormammu- purification and dark hole stop her projectiles. He also has a better damage output. He does not need to rush her down so he cuts her options.
Zero- Now this is not really bad its pretty even but, his buster will stop a lot of things ie. All projectiles and traps(minus hopscotch). His little teleport dash will go over hopscotch. There damage output is about the same, but his mixup is better.
Super Skrull- Better damage can do that dive to get around zoning. Now I need to test this but I think you can set a peekaboo and stand under it and it should stop the dive punch.
Modok- His zoning just flat out rapes her.
Taskmaster- He beats Trish in every fashion of the game.
Captain America- Equal damage, but since he can throw his shield at different angles it makes Trish’s zoning very hard.
Dante- Better damage. Can out zone her in a sense. Has a teleport to get around traps.
Amaterasu- Has better ground normals. Her super makes her think twice about zoning and Ammy super punishes air dashes since it has crappy recovery.
Spencer- Can get in and stay on Trish. Has way better damage. Must I say it Bionic Arm will shut anything down that is done on the ground.
Wolverine- He is cheap lol. Crazy high damage. moves so fast that hopscotch does not slow him down. You can dive kick a peekaboo.
Deadpool-Same as Modok, but deadpool’s damage is way better.
Magneto- Her worst match-up by far imo. Just like taskmaster he beats her for free.
X-23- She can get around the zoning but damage is not better than Trish’s.
Phoenix- Can out zone her and has a teleport.
Arthur- Like deadpool and Modok will beat her from the other side of the screen.
Now if Trish wants to beat all these bad match ups you will need superb assist play and the ability to move around the screen to avoid assist and attacks. It seems simple but rather tough to do.