You want a good quality motherboard. Your choice will depend on which processor you purchase, AMD or Intel.
What kind of gaming do you do now, and in the foreseeable future? AMDs have great value, but Intels perform better. Also, AMD has a history of keeping the same socket type across generations so it’s much easier to upgrade. Other than that, there is absolutely no difference.
My personal view is that only hardcore enthusiasts should get an Intel chip for now. Unless you benchmark and push your system to the very limit, you will never be able to tell a difference in performance, and the price is much cheaper. People who absolutely want the best performance, however, should go with an Intel.
This is what makes a good motherboard:
https://www.youtube.com/watch?v=cIED0pzwBT0
The MOSFET design is one of the first things I look at on a motherboard I want to buy. 90% of the time it’s the MOSFETs or capacitors that blow, causing mobo failure. I there are 8+2 phase designs out now and I wish I had gone with that one, since I eventually want to overclock my CPU to max air cooling.
Here is the board I bought, the ASRock 990FX Extreme3:
Spoiler
http://i.imgur.com/V9Mu6GB.jpg
See the area I highlighted? Those are the MOSFETs, and on this board The MOSFET phase design is 3 + 2 which is not sufficient for maximum overclocking. If I did that and ran it 24-7, chances are they will eventually fail prematurely.
This is what I should have gotten, the GIGABYTE GA-990FXA-UD3:
Spoiler
http://i.imgur.com/IpVNgbY.jpg
Much better. It has an 8 + 2 phase design, which is much better for overclocking. You can go with much higher voltages and not risk failing because there are more phases, and hence less power going through each MOSFET at any given time. They won’t melt or blow quite as easily. Also, that board has a nice heatsink and heatpipe on both the MOSFETS and the VRM controller (the yellow highlighted area). That’s really nice to have.
Those boards aren’t that far apart in price either. The GIGABYTE is only like $20 more. I’m sticking with this board for now, and when I finally get around to installing my 8350 CPU (It’s still sitting in the box 'cause I’m lazy. LOL), I will overclock it just a bit. Not maxed out like I had planned on.
Anyway, that’s some stuff to look for. Get on an overclocking board like Overclock.net. They have a really knowledgeable community that can teach you all about not only overclocking, but also PC maintenance and health as well. Also, how to stay away from bullshit like what I bought. that board was marketed as an overclocking board, but it’s clearly not. The TomsHardware forums are also really good, but they aren’t as specialized.
Good luck on your builds and feel free to PM if you got any questions or need some help.