I think Drew benefits a lot off of his teams and online when I face him, heh. Movement is pretty important, and is something I make a point to practice, since I can’t plink. Those wavedashes and aerial movement has to be on point lol. I’m trying to get my cr.H hopping down (something I’ve yet to see anyone implement, and I think it’s a pretty powerful mixup tool).
brainpipe gave a good overview of those matchups. I’ll just add that playing the air game against Wesker along with using your assists is pretty effective against Wesker. Sitting under an L bomb in the Skrull matchup is great, since that deters random meteor smashes. Bombs are great against characters with good aerial mobility or teleports in general, while they aren’t as necessary against more ground based opponents.