This is probably the deepest fighter you will ever play. Even as deep as Blazblue.
How do you play this game? Well, how do you play SF4, Blazblue and SSBB? It is more or less the same. The only exceptions are DemonHyo (plays MSP in MVC2, and Blanka in SF4) and me (not a pro like DemonHyo, but i count lol. I play Abel, Ken, DeeJay, and Balrog in SF4 and play Scrub and Team Z in MVC2). How you play in other fighters are pretty much similar.
Practice everything you want to know about a top tier character (if you wanna be competitive). If you wanna make a statement like VDO, focus on a low tier character and learn the strengths, weaknesses, and combos with that character.
Get that slow paced mentallity out of your head. This game is fast as hell, so be prepared to think quickly.
First thing to do is to learn how to block. In MVC2, not blocking can kill you extremely quickly. You also got to learn how to get people not to block. Guard breaks, cross-ups, and unblockables are the major ways. to get people to not block. Also try something called mind-fucking lol. Trick them into thinking one thing, and get them as a result.
Characters that I started with to learn the higher marvel portion (started with low-tier) were Storm/Sent/Cable AKA Team Sheild(?). This team teaches everything you need to learn. It teaches you to run away to build meter, rushdown, trap, keepaway, and the gods in general. If you want to start with Magneto, Magneto/Cable/Sent is the team to start with AKA Team Row. This teaches you how to rushdown with Magneto, Keepaway without the help of assist, and how to do quick damaging fast fly combos.
Basics= Runaway, Rushdown, Keepaway, and Trap
Runaway is when you run away using normals to build meter
Rushdown is when you attempt to get your opponent to stop blocking and pressure the hell out of him
Trap is when you keep someone blocking and chip them for major damage. If they don’t block they get hit by a combo.
Keepaway is when you use long range attacks to “keepaway” from your opponent.
Basic stuff you should learn for higher marvel is: Fly/Unfly, Fastfly, Runaway, Keepaway, Traps (spiral trap, Strider/Doom, Sent/Capcom, Jin/Doom (whoops! lol), etc.), ROM infinite, IM infinite, etc.
Hoped I helped 