Runes for Nidalee are Armor Pen/ Dodge or Armor (dodge is preferable because she gains dodge in kitty form)/ Cooldowns/ Whatever quints. Nidalee shouldn’t get Sorc shoes, so the 9 MPen isn’t worth it, and the armor pen helps you much more early game.
Level one should be heal, then trap at 2. Level heal first, then spear. Do not use spear at all in lane, just heal and last hit and harass. At level 6 you become a real character. Roll up on some bitches with kitty form. You should be able to outlane just about anyone in the game.
Depending on when you have to go back you should either get sheen first, then rageblade, then lichbane, or just get your Rabadon’s first and skip the Reageblade and get Lichbane.
There are two core builds with Nidalee:
Doran’s Ring -> Sheen -> Rageblade -> Lichbane ->Rabadon’s -> Void Staff-> Zhonya’s
Doran’s Ring -> Rabadon’s -> Lichbane -> Void Staff -> Zhonya’s -> (I don’t even know what you would get at this point, lol. GA I guess, lol)
Always get Merc Treads. Conceivably there could be a team where Ninja Tabi would be better, but just always get Merc Treads, for real.
There are games where you will want Banshee’s, but Nidalee’s maneuverability is her survivability, and you shouldn’t be jumping into the middle of teamfights. She is good at poking, healing, and finishing. Also fucking split-pushing. Nidalee does that better and safer than most characters. To give you an idea, I think I have seen Hotshot get Banshee’s precisely once on Nidalee, and they had like 3 fed AP casters. I don’t think it should be included in a core build. If there is a mobile blink-type character who can blow you up in one combo, then get it. Otherwise just get more AP.
As far as the blue buff thing goes, shorter cooldown on AP caster nukes is WAY scarier than more bandage tosses, lol. It’s not even a comparison. As far as his ult is concerned, just don’t fight when it’s down. I mean, if your AP carry is a feeder and not helpful, maybe, but in a real game the AP carry should always get it, and the support should get any second blues you steal, if possible.
//EDIT\
Ghost/Flash on Nidalee. I don’t know when the last time you saw Hotshot play, but he has never run ignite on Nidalee that I have seen. Hell, he rages on Nidalee’s who take anything other than Ghost/Flash. Ghost/Flash is just way too strong for her.